2008

1. Novel derivatives of psammaplin A, a method for their synthesis and their use for the prevention or treatment of cancer
   Gronemeyer, Hinrich; Altucci, Lucia; De Lera, Angel; Stunnenberg, Hendrik Gerard
   • PCT/IB2008/001887 (pub. 2008/10/23), WO2008125988-56pp
2. Derivatives of psammaplin A, a method for their synthesis and their use for the prevention or treatment of cancer
   Gronemeyer, Hinrich; De Lera, Angel; Altucci, Lucia
   • Eur. Pat. Appl. 07290253.9 (published 2008/09/03, Bulletin 2008/36), EP1964835A1-32pp
3. Expedient Total Syntheses of WIN 64745 and WIN 64821
   Carlos Pérez-Balado and Angel R. de Lera
   • Org Lett. 2008 Sep 4;10(17):3701-4
4. New retinoid chemotypes: 9-cis-Retinoic acid analogs with hydrophobic rings derived from terpenes as selective RAR agonists
   Susana Álvarez, Yolanda Pazos-Randulfe, Harshal Khanwalkar, Pierre Germain, Rosana Álvarez, Hinrich Gronemeyer, and ángel R. de Lera
   • Bioorg Med Chem. 2008 Nov 15;16(22):9719-28
5. Stereoselective Stille Coupling of Enantiopure Haloallenes and Alkenylstannanes for the Synthesis of Allenyl Carotenoids. Experimental and Computational Studies
   Belén Vaz, Raquel Pereira, Martín Pérez, Rosana Álvarez, Angel R. de Lera
   • J. Org. Chem., 2008, 73(17), 6534-6541
6. Nuclear receptor ligand binding domains: reduction of helix H12 dynamics to favor crystallization
   Virginie Nahoum, Alexandra Lipski, Fabien Quillard, Jean-François Guichou, Yvan Boublik, Efrén Pérez, Pierre Germain, Angel R. de Lera, and William Bourguet
   • Acta Cryst. Sect. F , 2008, F64, 614-616
7. Inhibition of IκB Kinaseβ and Anticancer Activities of Novel Chalcone Adamantyl Arotinoids
   Paula Lorenzo, Rosana Alvarez, Maria A. Ortiz, Susana Alvarez, F. Javier Piedrafita and Angel R. de Lera
   • J. Med. Chem., 51 (17), 5431–5440, 2008
8. The Associative Transmetalation in the Stille Cross-Coupling Reaction to Form Dienes: Theoretical Insights into the Open Pathway
   Rosana Álvarez, Martín Pérez, Olalla Nieto Faza and Angel R. de Lera
   • Organometallics, 27 (14), 3378–3389, 2008
9. Synthesis of Benzamides Related to Anacardic Acid and Their Histone Acetyltransferase (HAT) Inhibitory Activities
   José A. Souto, Mariarosaria Conte, Rosana Álvarez, Angela Nebbioso, Vincenzo Carafa, Lucia Altucci, and Angel R. de Lera
   • ChemMedChem, Volume 3 Issue 9, Pages 1435 - 1442, 2008
10. Photochromic polymer films based on a 14-F bacteriorhodopsin derivative
    Anna Druzhko, Rosana Álvarez and Angel R. de Lera
    • J. Biomater. Sci. Polymer Edn, Vol. 19, No. 12, pp. 1585-1595 (2008)
11. Retinoic acid analogues inhibit Human Herpesvirus 8 replication
    Elisabetta Caselli, Galvan Monica, Fabio Santoni, Susana Alvarez, Angel R. de Lera, Diana Ivanova, Hinrich Gronemeyer, Arnaldo Caruso, Massimo Guidoboni, Enzo Cassai, Riccardo Dolcetti, and Dario Di Luca
    • Antiviral Therapy 2008, 13(2): 199-209
12. Stereospecificity of Retinol Saturase: Absolute Configuration, Synthesis and Biological Evaluation of Dihydroretinoids
    Alexander R. Moise, Marta Domínguez, Susana Alvarez, Rosana Alvarez, Michael Schupp, Ana G. Cristancho, Philip D. Kiser, Angel R. de Lera, Mitchell A. Lazar, Krzysztof Palczewski
    • J. Am. Chem. Soc., 2008, 130(4), 1154-1155
13. Characterization of the Switch in the Mechanism of an Intramolecular Diels-Alder Reaction
    Silva Lopez, Carlos; Nieto Faza, Olalla; de Lera, Angel R.
    • Journal of Organic Chemistry (2008), 73(2), 467-473
14. Mechanistic Insights into the Stereocontrolled Synthesis of Hexahydropyrrolo[2,3-b]indoles by Electrophilic Activation of Tryptophan Derivatives
    Silva Lopez, Carlos; Perez-Balado, Carlos; Rodriguez-Grana, Paula; de Lera, Angel R.
    • Organic Letters, 10 (1), 77 -80, 2008