2007

1. Structural basis for the high all-trans retinaldehydr reductase activity of the tumor marker AKR1B10
   Oriol Gallego, F. Xavier Ruiz, Albert Ardèvol, Marta Domínguez, Rosana Alvarez, Angel R. de Lera, Carme Rovira, Jaume Farrés, Ignacio Fita and Xavier Parés
   • Proceedings of the National Academy of Sciences of the United States of America, (2007), 104(52), 20764
2. Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function
   Nahoum, Virginie; Perez, Efren; Germain, Pierre; Rodriguez-Barrios, Fatima; Manzo, Fabio; Kammerer, Sabrina; Lemaire, Geraldine; Hirsch, Oliver; Royer, Catherine A.; Gronemeyer, Hinrich; de Lera, Angel R.; Bourguet, William
   • Proceedings of the National Academy of Sciences of the United States of America (2007), 104(44), 17323-17328
3. Deuterium exchange and mass spectrometry reveal the interaction differences of two synthetic modulators of RXRa LBD
   Yan, Xuguang; Perez, Efren; Leid, Mark; Schimerlik, Michael I.; De Lera, Angel R.; Deinzer, Max L.
   • Protein Science (2007), 16(11), 2491-2501
4. Rapid, nongenomic actions of retinoic acid on phosphatidylinositol-3-kinase signaling pathway mediated by the retinoic acid receptor
   Masia, Susana; Alvarez, Susana; de Lera, Angel R.; Barettino, Domingo
   • Molecular Endocrinology (2007), 21(10), 2391-2402
5. RAR and RXR modulation in cancer and metabolic disease
   Altucci, Lucia; Leibowitz, Mark D.; Ogilvie, Kathleen M.; de Lera, Angel R.; Gronemeyer, Hinrich
   • Nature Reviews Drug Discovery (2007), 6(10), 793-810
6. Design of selective nuclear receptor modulators: RAR and RXR as a case study
   de Lera, Angel R.; Bourguet, William; Altucci, Lucia; Gronemeyer, Hinrich
   • Nature Reviews Drug Discovery (2007), 6(10), 811-820
7. Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities
   Bontempo, Paola; Mita, Luigi; Miceli, Marco; Doto, Antonella; Nebbioso, Angela; De Bellis, Floriana; Conte, Mariarosaria; Minichiello, Annunziata; Manzo, Fabio; Carafa, Vincenzo; Basile, Adriana; Rigano, Daniela; Sorbo, Sergio; Castaldo Cobianchi, Rosa; Schiavone, Ettore Mariano; Ferrara, Felicetto; De Simone, Mariacarla; Vietri, MariaTeresa; Cioffi, Michele; Sica, Vincenzo; Bresciani, Francesco; de Lera, Angel R.; Altucci, Lucia; Molinari, Anna Maria
   • International Journal of Biochemistry & Cell Biology (2007), 39(10), 1902-1914
8. Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor
   Alvarez, Susana; Germain, Pierre; Alvarez, Rosana; Rodriguez-Barrios, Fatima; Gronemeyer, Hinrich; De Lera, Angel R.
   • International Journal of Biochemistry & Cell Biology (2007), 39(7-8), 1406-1415
9. Electrocyclic ring opening of cis-bicyclo[m.n.0]alkenes: the anti-Woodward-Hoffmann quest
   Lopez, Carlo Silva; Faza, Olalla Nieto; de Lera, Angel R.
   • Chemistry--A European Journal (2007), 13(17), 5009-5017
10. A density functional theory study of the stille cross-coupling via associative transmetalation. The role of ligands and coordinating solvents
    Alvarez, Rosana; Faza, Olalla Nieto; de Lera, Angel R.; Cardenas, Diego J.
    • Advanced Synthesis & Catalysis (2007), 349(6), 887-906
11. Pseudopericyclic design drives antara-antara [1,5] methylene sigmatropic shifts from a stepwise to a concerted mechanism
    Lopez, Carlos Silva; Faza, Olalla Nieto; Souto, Jose A.; Alvarez, Rosana; De Lera, Angel R.
    • Journal of Computational Chemistry (2007), 28(8), 1411-1416
12. Bimetallic Intermediates in the Formation of Nucleophilic Allenylzincs from Allenylpalladiums: A DFT Study
    Alvarez, Rosana; De Lera, Angel R.; Aurrecoechea, Jose M.; Durana, Aritz
    • Organometallics (2007), 26(11), 2799-2802
13. Bispyridinium Dienes: Histone Deacetylase Inhibitors with Selective Activities
    Perez-Balado, Carlos; Nebbioso, Angela; Rodriguez-Grana, Paula; Minichiello, Annunziata; Miceli, Marco; Altucci, Lucia; de Lera, Angel R.
    • Journal of Medicinal Chemistry (2007), 50(10), 2497-2505
14. Cyclopent-2-en-1-one derivatives as PPAR modulators, their preparation, pharmaceutical and cosmetic compositions, and uses thereof
    De Lera, Angel Rodriguez; Otero Cabredo, Maria Paz
    • PCT Int. Appl. (2007), 63pp. WO2007029121 A2 20070315
15. Sulfoxide-Induced Stereoselection in [1,5]-Sigmatropic Hydrogen Shifts of Vinylallenes. A Computational Study
    Faza, Olalla Nieto; Lopez, Carlos Silva; de Lera, Angel R.
    • Journal of Organic Chemistry (2007), 72(7), 2617-2624
16. Total synthesis of peridinin and related C37-norcarotenoid butenolides
    Vaz, Belen; Dominguez, Marta; Alvarez, Rosana; de Lera, Angel R.
    • Chemistry--A European Journal (2007), 13(4), 1273-1290
17. Preparation of cyclopent-2-en-1-one derivatives as PPAR modulators and their use in cosmetic and pharmaceutical compositions
    De Lera, Angel Rodriguez; Otero, Cabredo Maria Paz
    
    
    • Fr. Demande (2007), 56pp. FR2888846 A1 20070126
18. Specificity of Zebrafish Retinol Saturase: Formation of All-trans-13,14-dihydroretinol and All-trans-7,8-dihydroretinol
    Moise, Alexander R.; Isken, Andrea; Dominguez, Marta; De Lera, Angel R.; Von Lintig, Johannes; Palczewski, Krzysztof
    
    • Biochemistry (2007), 46(7), 1811-1820